If you have colitis, you may also feel abdominal pain related to cramping. The reason for this is because there’s inflammation in the lining of your colon or large intestine. You may experience pain ranging from mild to severe, which will stop as your diarrhea recedes. 

Often, experts will advise you to avoid NSAIDs meant for easing your stomach pain. Instead, they’d recommend you to take an antispasmodic medicine with guidance from your physician.